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Discovery and engineering of novel enzymes for synthesis of new moleculars

  1. Regioselective and enantioselective hydroxylation of propargylic C-H bonds are useful reactions but often lack appropriate catalysts. Here a green and efficient asymmetric hydroxylation of primary and secondar...

    Authors: Xu Deng, Cheng-Cheng Song, Wen-Jing Gu, Yu-Jie Wang, Lu Feng, Xiao-Jian Zhou, Ming-Qiang Zhou, Wei-Cheng Yuan and Yong-Zheng Chen
    Citation: Bioresources and Bioprocessing 2024 11:64
  2. Esterases are crucial biocatalysts in chiral compound synthesis. Herein, a novel esterase EstSIT01 belonging to family V was identified from Microbacterium chocolatum SIT101 through genome mining and phylogenetic...

    Authors: Xinjia Li, Haoran Yu, Shengli Liu, Baodi Ma, Xiaomei Wu, Xuesong Zheng and Yi Xu
    Citation: Bioresources and Bioprocessing 2024 11:59
  3. Prediabetes is an important stage in the development of diabetes. It is necessary to find a safe, effective and sustainable way to delay and reverse the progression of prediabetes. Akkermansia muciniphila (A. muc...

    Authors: Shuai Yan, Lin Chen, Na Li, Xiaohui Wei, Jingjing Wang, Weiping Dong, Yufan Wang, Jianxia Shi, Xiaoying Ding and Yongde Peng
    Citation: Bioresources and Bioprocessing 2024 11:51
  4. Pectin lyase (PMGL) is an industrially important enzyme with widespread applications in the food, paper, and textile industries, owing to its capacity for direct degradation of highly esterified pectin. In thi...

    Authors: Junyi Li, Manli Yang, Fengguang Zhao, Yaping Zhang and Shuangyan Han
    Citation: Bioresources and Bioprocessing 2024 11:37
  5. Unspecific peroxygenases (UPOs) are glycosylated enzymes that provide an efficient method for oxyfunctionalizing a variety of substrates using only hydrogen peroxide (H2O2) as the oxygen donor. However, their poo...

    Authors: Xin Fu, Kexin Lin, Xiaodong Zhang, Zhiyong Guo, Lixin Kang and Aitao Li
    Citation: Bioresources and Bioprocessing 2024 11:33
  6. The Thermomyces lanuginosus lipase (TLLs) was successfully immobilized within a novel hydrogel matrix through a two-step crosslinking method. TLLs were initially crosslinked through the Schiff base reaction by ox...

    Authors: Ming Chen, Weina She, Xin Zhao, Cheng Chen, Benwei Zhu, Yun Sun and Zhong Yao
    Citation: Bioresources and Bioprocessing 2024 11:7
  7. Cytidine triphosphate (CTP), as a substance involved in the metabolism of phospholipids, proteins and nucleic acids, has precise drug effects and is a direct precursor for the synthesis of drugs such as citico...

    Authors: Zonglin Li, Yahui Zhong, Zhoulei Qing and Zhimin Li
    Citation: Bioresources and Bioprocessing 2024 11:6
  8. Aminoacyl-tRNA synthetase (aaRS) is a core component for genetic code expansion (GCE), a powerful technique that enables the incorporation of noncanonical amino acids (ncAAs) into a protein. The aaRS with poly...

    Authors: Ke Liu, Ling Jiang, Shuang Ma, Zhongdi Song, Lun Wang, Qunfeng Zhang, Renhao Xu, Lirong Yang, Jianping Wu and Haoran Yu
    Citation: Bioresources and Bioprocessing 2023 10:92